ATG18

Symbol: ATG18
Alias: AUT10;CVT18;NMR1;SVP1
Entrez gene ID: 850577
Ensembl gene ID: YFR021W
Species: Yeast (Taxid: 4932)

Functional description:
Atg18p; Phosphoinositide binding protein required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; binds both phosphatidylinositol (3,5)-bisphosphate and phosphatidylinositol 3-phosphate; WD-40 repeat protein [Source:SGD;Acc:S000001917] [Ensembl]

Observation:

The replicative lifespan of ATG18 deletion mutant is not shorter than that of wild-type under DR [18690010].



Interventions:
  • ATG18 deletion

  • Assays: Replicative Lifespan

    Classification:
  • No Age Effect


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • WIPI2 (9606)
  • WIPI2 (9615)
  • WIPI2 (9913)
  • Wipi2 (10090)
  • Wipi2 (10116)
  • WIPI2 (9031)
  • Atg18 (7227)
  • AgaP_AGAP005910 (7165)
  • atg-18 (6239)
  • SPAC589.07c (4896)
  • ATG18 (4932)
  • KLLA0D04664g (28985)
  • AGOS_AAL119W (33169)
  • GeneID:2676412 (148305)
  • NCU03441 (5141)
  • AtATG18b (3702)
  • Os02g0791800 (4530)



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