gsa-1

Symbol: gsa-1
Entrez gene ID: 171687
Ensembl gene ID: R06A10.2
Species: Worm (Taxid: 6239)

Functional description:
Protein GSA-1; G protein, Subunit Alpha family member (gsa-1) [Source:RefSeq peptide;Acc:NP_490817] [Ensembl]; The gsa-1 gene encodes a Gs alpha subunit of heterotrimeric G proteins which affects L1 larval stage viability, movement, and egg laying; it is genetically upstream of sgs-1 with respect to neuronal degeneration, as defined by gain-of-function analysis, and is expressed in excitable cells. [WormBase]

Observation:

RNAi against R06A10.2 decreases mean and maximum lifespan by 83-85% and 48%, respectively [18059442].



Interventions:
  • gsa-1 RNAi -83-85% -48%

  • Assays: Organismal Lifespan

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • GNAS (9606)
  • GNAS (9598)
  • GNAS (9615)
  • GNAS (9913)
  • GNAS (9031)
  • gnas (7955)
  • G-salpha60A (7227)
  • AgaP_AGAP012095 (7165)
  • gsa-1 (6239)



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