Denigma

pkc-3

Symbol: pkc-3
Name: Protein Kinase C
Alias: Protein Kinase C family member (pkc-3);WBGENE00004034
Entrez gene ID: 173914
Ensembl gene ID: F09E5.1
Species: Worm (Taxid: 6239)

Functional description:
Required for the normal progression of embryogenesis and viability of the organism. Plays an indispensable role in establishing embryonic polarity and in recruiting and maintaining par-6 to the periphery, through interaction with par-3. Required for epithelial cell polarity in the distal spermatheca. Phosphorylates serine residues of num-1. [UniProt]

Observation:

pkc-3 RNAi in the adulthood extends the lifespan [New longevity regulators].



Interventions:
  • pkc-3 RNAi

    • Assays: Organismal Lifespan

    Classification:

    Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • PRKCI (9606)
  • PRKCI (9598)
  • PRKCI (9615)
  • PRKCI (9913)
  • Prkci (10090)
  • Prkci (10116)
  • PRKCI (9031)
  • prkci (7955)
  • aPKC (7227)
  • pkc-3 (6239)



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