Denigma: Factor

pat-3

Symbol: pat-3
Name: Paralysed Arrest at Two-fold 3
Alias: Paralysed Arrest at Two-fold family member (pat-3);WBGENE00003930
Entrez gene ID: 175504
Ensembl gene ID: ZK1058.2
Species: Worm (Taxid: 6239)

Functional description:
Possible role in cell-cell interactions. Integrin alpha pat-1/beta pat-3 is a receptor for laminin. Integrin alpha pat- 2/beta pat-3 recognizes the sequence R-G-D in its ligands (By similarity). [UniProt]

Observation:

pat-3 RNAi in the adulthood decreases mean and maximum lifespan by 28% and 50%, respectively [23144747].

Interventions:

pat-3 RNAi -28.1% -50.0%

Assays: Organismal Lifespan
Mean: -28.1
Maximum: -50.0

Classification:

Aging-Suppressor

Negative Aging-Suppressor

References:

23144747: Prediction of C. elegans Longevity Genes by Human and Worm Longevity Networks.

Aging Relevance Analysis/Source:

GenAge