zyg-11

Symbol: zyg-11
Name: ZYGote defective: embryonic lethal
Alias: ZYGote defective: embryonic lethal family member (zyg-11);WBGENE00006996
Entrez gene ID: 174284
Ensembl gene ID: C08B11.1
Species: Worm (Taxid: 6239)

Functional description:
Acts as target recruitment subunit in the E3 ubiquitin ligase complex zyg-11-cul-2-elc-1. Required for metaphase to anaphase transition and M phase exit at meiosis II. Regulates polarity establishment. [UniProt]

Observation:

zyg-11 RNAi in the adulthood extends the lifespan [New longevity regulators].



Interventions:
  • zyg-11 RNAi

  • Assays: Organismal Lifespan

    Classification:

    Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • ZYG11B (9606)
  • ZYG11B (9598)
  • ZYG11B (9615)
  • ZYG11B (9913)
  • Zyg11b (10090)
  • Zyg11b (10116)
  • ZYG11B (9031)
  • si:ch211-11m18.3 (7955)
  • zyg-11 (6239)



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