Denigma: Factor

rps-14

Symbol: rps-14
Name: Ribosomal Protein, Small subunit
Alias: Ribosomal Protein;Small subunit family member (rps-14);WBGENE00004483
Entrez gene ID: 176006
Ensembl gene ID: F37C12.9
Species: Worm (Taxid: 6239)

Functional description:
Protein RPS-14; 40S ribosomal protein S14 [Source:UniProtKB/Swiss-Prot;Acc:P48150] [Ensembl]

Observation:

rps-14 RNAi in the adulthood extends mean and maximum lifespan by 17 and 22% [23144747]. Knockdown of rps-14 via RNAi started after the animal reached the late L4 stage extends lifespan by 6-19% [22103665].

Interventions:

rps-14 RNAi +6 to +19% +21.7%

Assays: Organismal Lifespan
Mean: +6 to +19
Maximum: +22

Classification:

Gerontogene

Positive Gerontogene

References:

22103665: Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan.

23144747: Prediction of C. elegans Longevity Genes by Human and Worm Longevity Networks.

Aging Relevance Analysis/Source:

GenAge