Denigma: Factor

rrt-1

Symbol: rrt-1
Name: aRginyl aa-tRNA syntheTase
Alias: aRginyl aa-tRNA syntheTase family member (rrt-1);WBGENE00004679
Entrez gene ID: 175659
Ensembl gene ID: F26F4.10
Species: Worm (Taxid: 6239)

Functional description:
Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis (By similarity). [UniProt]

Observation:

rrt-1 RNAi in the adulthood extends the lifespan [New longevity regulators]. Kockdown of rrt-1 via RNAi started after the animal reached the late L4 stage increases lifespan by 15-27% [22103665].

Interventions:

rrt-1 RNAi +15 to +27%

Assays: Organismal Lifespan

Classification:

Gerontogene

Positive Gerontogene

Aging Relevance Analysis/Source:

GenAge