Denigma

pat-2

Symbol: pat-2
Name: Paralysed Arrest at Two-fold
Alias: Paralysed Arrest at Two-fold family member (pat-2);WBGENE00003929
Entrez gene ID: 176240
Ensembl gene ID: F54F2.1
Species: Worm (Taxid: 6239)

Functional description:
Required for distal tip cell migration and dorsal pathfinding. Postulated to have a role in cell motility. Possible role in cell-cell interactions (By similarity). [UniProt]

Observation:

pat-2 RNAi in the adulthood extends the lifespan [New longevity regulators].



Interventions:
  • pat-2 RNAi

    • Assays: Organismal Lifespan

    Classification:

    Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • ITGA8 (9606)
  • ITGA8 (9598)
  • ITGA8 (9615)
  • Itga8 (10090)
  • RGD1564327 (10116)
  • ITGA8 (9031)
  • pat-2 (6239)



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