Denigma: Factor

fkb-6

Symbol: fkb-6
Name: FK506-Binding protein family 6
Alias: FK506-Binding protein family member (fkb-6);WBGENE00001431
Entrez gene ID: 180371
Ensembl gene ID: F31D4.3
Species: Worm (Taxid: 6239)

Functional description:
Protein FKB-6; FK506-Binding protein family member (fkb-6) [Source:RefSeq peptide;Acc:NP_508026] [Ensembl]; fkb-6 encodes a peptidyl-prolyl cis-trans isomerase that is most closely related to mammalian FK506-binding protein 4; loss of fkb-6 activity via large-scale RNAi screens indicates that fkb-6 is required fro embryonic and vulval development. [WormBase]

Observation:

fkb-6 RNAi in the adulthood extends the mean lifespan by 2.9% [New longevity regulators].

Interventions:

fkb-6 RNAi +2.4%

Assays: Organismal Lifespan

Classification:

Gerontogene

Positive Gerontogene

Aging Relevance Analysis/Source:

GenAge