Denigma

F35G12.4

Symbol: F35G12.4
Name: beta-transducin
Alias: WBGene00009441
Entrez gene ID: 175600
Ensembl gene ID: F35G12.4
Species: Worm (Taxid: 6239)

Functional description:
Regulator of deubiquitinating complexes. Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate (By similarity). [UniProt]

Observation:

RNAi against F35G12.4 starting in the adulthood decreases the lifespan [New longevity regulators].



Interventions:
  • F35G12.4 RNAi

    • Assays: Organismal Lifespan

    Classification:

    Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • WDR48 (9606)
  • WDR48 (9598)
  • WDR48 (9615)
  • WDR48 (9913)
  • Wdr48 (10090)
  • Wdr48 (10116)
  • WDR48 (9031)
  • wdr48 (7955)
  • LOC100333793 (7955)
  • CG9062 (7227)
  • beta-transducin (6239)
  • AT3G05090 (3702)
  • Os12g0165000 (4530)



    • Edit \ Update (Admin) | Delete

    Comment on This Data Unit