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Symbol: age-2 Species: Worm (Taxid: 6239) Observation: Homocygous age-2 mutation increases mean (+43%, +31%, +38%) and maximum (+29%, +36%, +18%)) lifespan by about 20%. age-2 mutant exhibit normal motility, slightly higher swimming rates, reduced fertility and somewhat longer development times and slightly larger size at the first egg laying. Lifespan is extended by reducing the initial mortality rate. age-2 mutation complements other aging gene mutations such as age-1, daf-2, spe-26, clk-1, clk-3 and gro-1. A age-1 age-2 double mutant lives longer than animals with individual mutations and exhibits a longer lifespan at 25 degree Celsius than at 20 degree Celsius [10219000]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRNote: Gene was not yet mapped. Can you figure out to which gene does this mutant belong to? Edit \ Update (Admin) | Delete |
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