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Symbol: GSH1 Name: glutathione (GSH) 1 Entrez gene ID: 853344 Ensembl gene ID: YJL101C Species: Yeast (Taxid: 4932) Functional description: Gsh1p; Gamma glutamylcysteine synthetase catalyzes the first step in glutathione (GSH) biosynthesis; expression induced by oxidants, cadmium, and mercury [Source:SGD;Acc:S000003637] [Ensembl] Observation: Deletion of GSH1 confers deficiency in glutathione biosynthesis and further increases chronological lifespan under 0.5% glucose restriction, but does not extend chronological lifespan under 2% glucose [18840459]. Therefore, GSH1 has a positive interaction with DR [18840459]. Interventions: Assays: Replicative Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Orthologs Edit \ Update (Admin) | Delete |
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