NFU1

Symbol: NFU1
Name: NifU-like protein 1
Alias: YKL040C; NUB1
Entrez gene ID: 853826
Ensembl gene ID: YKL040C
Species: Yeast (Taxid: 4932)

Functional description:
Mitochondrial matrix protein, involved in iron-sulfur complex biogenesis.; Nfu1p; Protein involved in iron metabolism in mitochondria; similar to NifU, which is a protein required for the maturation of the Fe/S clusters of nitrogenase in nitrogen-fixing bacteria [Source:SGD;Acc:S000001523] [Ensembl]

Observation:

NFU1 mutation slightly shortens the chronological lifespan under AL and the chronological lifespan of NFU1 mutants is not extended by 0.5% glucose DR [20421943].



Interventions:
  • NFU1 deletion

  • Assays: Chronological Lifespan

    Classification:
  • DR-Essential


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • NFU1 (9606)
  • NFU1 (9598)
  • NFU1 (9615)
  • NFU1 (9913)
  • Nfu1 (10090)
  • Nfu1 (10116)
  • NFU1 (9031)
  • hirip5 (7955)
  • CG32857 (7227)
  • CG33502 (7227)
  • CG32500 (7227)
  • AgaP_AGAP000598 (7165)
  • lpd-8 (6239)
  • SPBC1709.19c (4896)
  • NFU1 (4932)
  • KLLA0F25476g (28985)
  • AGOS_ABR045W (33169)
  • GeneID:2685166 (148305)
  • NCU01779 (5141)
  • NFU4 (3702)
  • NFU5 (3702)
  • Os05g0155300 (4530)

  • Orthologs
  • CG33502 (7227)
  • lpd-8 (6239)
  • Nfu1 (10090)
  • CG32500 (7227)
  • CG32857 (7227)
  • Nfu1 (10116)
  • SPBC1709.19c (4896)
  • NFU1 (9606)
  • CG33502 (7227)
  • lpd-8 (6239)
  • Nfu1 (10090)
  • CG32500 (7227)
  • CG32857 (7227)
  • Nfu1 (10116)
  • SPBC1709.19c (4896)
  • NFU1 (9606)



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