Denigma

ATG2

Symbol: ATG2
Name: AuTophaGy related 2
Alias: SPO72; AUT8; APG2
Entrez gene ID: 855479
Ensembl gene ID: YNL242W
Species: Yeast (Taxid: 4932)

Functional description:
Atg2p; Peripheral membrane protein required for vesicle formation during autophagy, pexophagy, and the cytoplasm-to-vaucole targeting (Cvt) pathway; involved in Atg9p cycling between the phagophore assembly site and mitochondria [Source:SGD;Acc:S000005186] [Ensembl]

Observation:

ATG2 deletion prevents chronological lifespan extension induced by amino-acid DR [20421943].



Interventions:
  • ATG2 deletion

    • Assays: Chronological Lifespan

    Classification:
  • DR-Essential


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • ATG2 (4932)
  • KLLA0D19899g (28985)
  • AGOS_ABL208W (33169)

    • Orthologs
  • Atg2 (7227)
  • Atg2a (10090)
  • Atg2b (10090)
  • ATG2B (9544)
  • atg-2 (6239)
  • ATG2A (9544)
  • Atg2a (10116)
  • ATG2A (9606)
  • ATG2B (9606)
  • Atg2 (7227)
  • Atg2a (10090)
  • Atg2b (10090)
  • ATG2B (9544)
  • atg-2 (6239)
  • ATG2A (9544)
  • Atg2a (10116)
  • ATG2A (9606)
  • ATG2B (9606)



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