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Symbol: faah-1 Name: Fatty Acid Amide Hydrolase 1 Entrez gene ID: 177613 Ensembl gene ID: B0218.1 Species: Worm (Taxid: 6239) Functional description: Protein FAAH-1; Protein FAAH-1, isoform a [Source:UniProtKB/TrEMBL;Acc:Q17449] [Ensembl] Observation: faah-1 overexpression reduces eicosapentaenoyl ethanolamide (EPEA), palmitoleyol ethanolamide, linoleyol ethanolamide, as well as arachidonoyl ethanolamide (AEA) levels, delays development, increases thermal stress resistance, and was associated with mean and maximum adult lifespan extension by 19 and 35%, respectively, in presence of abundant food but not under (two different protocols of) DR. Overexpression in pharynx was largely sufficient for this lifespan extension [21562563]. Interventions: Assays: Chronological Lifespan Mean: +19 Maximum: +35 Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Orthologs Edit \ Update (Admin) | Delete |
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