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Symbol: GUP1 Name: Glycerol UPtake 1 Entrez gene ID: 852796 Ensembl gene ID: YGL084C Species: Yeast (Taxid: 4932) Functional description: Gup1p; Plasma membrane protein involved in remodeling GPI anchors; member of the MBOAT family of putative membrane-bound O-acyltransferases; proposed to be involved in glycerol transport [Source:SGD;Acc:S000003052] [Ensembl] Observation: GUP1 deletion extends mean and maximum replicative lifespan by 32 and 30%, respectively, as well as chronological lifespan. DR-induced maximal replicative lifespan extension is not further increased by GUP1 deletion, while gup1 mutant displayed longer chronological lifespan under DR [21584246]. Interventions: Assays: Replicative Lifespan Chronological Lifespan Mean: +32 Maximum: +30 Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Orthologs Edit \ Update (Admin) | Delete |
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