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Symbol: VPS20 Name: Vacuolar Protein Sorting 20 Alias: VPL10; VPT20; CHM6 Entrez gene ID: 855101 Ensembl gene ID: YMR077C Species: Yeast (Taxid: 4932) Functional description: Vps20p; Myristoylated subunit of ESCRTIII, the endosomal sorting complex required for transport of transmembrane proteins into the multivesicular body pathway to the lysosomal/vacuolar lumen; cytoplasmic protein recruited to endosomal membranes [Source:SGD;Acc:S000004682] [Ensembl] Observation: VPS20 deletion decreases mean and maximum replicative lifespan by 16% and 19%, respectively, and additionally cancels out the DR-induced replicative lifespan extension [22912585]. Interventions: Assays: Replicative Lifespan Mean: -16 Maximum: -19 Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Orthologs Edit \ Update (Admin) | Delete |
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