URH1

Symbol: URH1
Name: URidine Hydrolase 1
Entrez gene ID: 852009
Ensembl gene ID: YDR400W
Species: Yeast (Taxid: 4932)

Functional description:
Urh1p; Uridine nucleosidase (uridine-cytidine N-ribohydrolase), cleaves N-glycosidic bonds in nucleosides; involved in the pyrimidine salvage and nicotinamide riboside salvage pathways [Source:SGD;Acc:S000002808] [Ensembl]

Observation:

Deletion of URH1 increases mean replicative lifespan by 24% [20550517].



Assays: Replicative Lifespan
Mean: +24

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • SPAC17G8.02 (4896)
  • URH1 (4932)
  • KLLA0C06721g (28985)
  • AGOS_AFR399W (33169)
  • GeneID:2676016 (148305)
  • NCU02055 (5141)



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