sck2

Symbol: sck2
Name: serine/threonine protein kinase Sck2
Entrez gene ID: 2541867
Ensembl gene ID: SPAC22E12.14c
Species: (Taxid: 4896)

Functional description:
Protein kinase that is part of growth control pathway which is at least partially redundant with the cAMP pathway.

Observation:

Deletion of sck3 increases maximum chronological lifespan by 200%. Deletion mutant accumulated less reactive oxygen species and had delayed initiation of apoptosis. Additional deletion of pka1 further extend the lifespan of sck3 mutants [16822282].



Assays: Chronological Lifespan
Maximum: +200

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • SGK3 (9606)
  • SGK3 (9598)
  • SGK3 (9615)
  • SGK3 (9913)
  • Sgk3 (10090)
  • SGK3 (9031)
  • sgk3 (7955)
  • sck2 (4896)

  • Note: Ortholog of human AKT1/2 and S6K?

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