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Symbol: TCB3 Name: Three Calcium and lipid Binding domains (TriCalBins) 3 Entrez gene ID: 854903 Ensembl gene ID: YML072C Species: Yeast (Taxid: 4932) Functional description: Tcb3p; Lipid-binding protein, localized to the bud via specific mRNA transport; non-tagged protein detected in a phosphorylated state in mitochondria; GFP-fusion protein localizes to the cell periphery; C-termini of Tcb1p, Tcb2p and Tcb3p interact [Source:SGD;Acc:S000004537] [Ensembl]; Lipid-binding ER protein, enriched at ER-plasma membrane contact sites; localized to the bud via specific mRNA transport; non-tagged protein detected in a phosphorylated state in mitochondria; C-termini of Tcb1p, Tcb2p and Tcb3p interact [SGD] Observation: Deletion of TCB3 increases mean and maximum chronological lifespan by 18 and 25%, respectively [22216232]. Assays: Mean: +18 Maximum: +25 Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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