HFM1

Symbol: HFM1
Name: Helicase Family Member 1
Alias: MER3
Entrez gene ID: 852641
Ensembl gene ID: YGL251C
Species: Yeast (Taxid: 4932)

Functional description:
Hfm1p; Meiosis specific DNA helicase involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control; catalyzes the unwinding of Holliday junctions; has ssDNA and dsDNA stimulated ATPase activity [Source:SGD;Acc:S000003220] [Ensembl]

Observation:

Deletion of HFM1 increases mean chronological lifespan by 19 - 139% (19, 30, 45, 139) in diploid cells [21447998].



Assays:
Mean: +19-139

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • HFM1 (4932)
  • KLLA0D11462g (28985)
  • GeneID:2684075 (148305)
  • NCU09793 (5141)



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