Denigma: Factor

ARO7

Symbol: ARO7
Name: AROmatic amino acid requiring 7
Alias: HGS1;OSM2;,TYR7
Entrez gene ID: 856173
Ensembl gene ID: YPR060C
Species: Yeast (Taxid: 4932)

Functional description:
Aro7p; Chorismate mutase, catalyzes the conversion of chorismate to prephenate to initiate the tyrosine/phenylalanine-specific branch of aromatic amino acid biosynthesis [Source:SGD;Acc:S000006264] [Ensembl]

Observation:

Under starvation/extreme DR deletion of ARO7 increases mean chronological lifespan and confers higher resistance to heat-shock, but made cell more sensitive to acetic acid and leads to growth defects. In W303-1A background ARO7 deletion causes an even more severe growth defect and mutants are short-lived [20657825].

Interventions:

ARO7 deletion

Assays: Chronological Lifespan

Classification:

Aging Associated

Aging Relevance Analysis/Source:

GenAge