RPL40A

Symbol: RPL40A
Name: Ribosomal Protein of the Large subunit 40A
Alias: CEP52A;UBI1;UB11;L40A
Entrez gene ID: 854658
Ensembl gene ID: YIL148W
Species: Yeast (Taxid: 4932)

Functional description:
Rpl40ap; Fusion protein, identical to Rpl40Ap, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes [Source:SGD;Acc:S000001802] [Ensembl]

Observation:

Deletion of RPL40A increases mean replicative lifespan by 20% in the ORF collection and by 37% in the remade strain [22377630].



Assays:
Mean: +20-37

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • UBA52 (9606)
  • UBA52 (9598)
  • UBA52 (9615)
  • UBA52 (9913)
  • Uba52 (10116)
  • uba52 (7955)
  • RpL40 (7227)
  • AgaP_AGAP007927 (7165)
  • ubq-2 (6239)
  • uep1 (4896)
  • ubi1 (4896)
  • RPL40A (4932)
  • RPL40B (4932)
  • KLLA0A00616g (28985)
  • AGOS_AFR285C (33169)
  • GeneID:2683931 (148305)
  • NCU05275 (5141)
  • UBQ1 (3702)
  • AT2G36170 (3702)
  • Os03g0234200 (4530)
  • PF13_0346 (5833)



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