ACT

Symbol: ACT
Name: ACTin
Alias: END7;ABY1;actin
Entrez gene ID: 850504
Ensembl gene ID: YFL039C
Species: Yeast (Taxid: 4932)

Functional description:
Act1p; Actin, structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions [Source:SGD;Acc:S000001855] [Ensembl]

Observation:

An ACT1 allele which reduces actin dynamics decreases chronological lifespan, while an allele that increases actin dynamics increases chronological lifespan by 32% [15024029].



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • ACTG1 (9606)
  • ACTG1 (9615)
  • ACTG1 (9913)
  • Actg1 (10090)
  • Actg1 (10116)
  • ACTG1 (9031)
  • actc1a (7955)
  • hm:zewp0073 (7955)
  • zgc:86709 (7955)
  • Act5C (7227)
  • AgaP_AGAP000651 (7165)
  • act-5 (6239)
  • act1 (4896)
  • ACT1 (4932)
  • KLLA0D05357g (28985)
  • AGOS_ABR222W (33169)
  • GeneID:2677355 (148305)
  • NCU04173 (5141)
  • ACT11 (3702)
  • Os05g0106600 (4530)



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