PGRP-LF

Symbol: PGRP-LF
Name: Peptidoglycan recognition protein LF
Entrez gene ID: 39064
Ensembl gene ID: FBgn0035977
Species: Fly (Taxid: 7227)

Functional description:
Peptidoglycan-recognition protein probably involved in innate immnunity by binding to peptidoglycans (PGN) of bacteria and activating the immune response. [UniProt]

Observation:

Overexpression of PGRP-LF increases mean and maximum lifespan by 13% and 24% [22366109].



Assays: Organismal Lifespan
Mean: +13
Maximum: +24

Classification:
  • Aging-Suppressor
  • Positive Aging-Suppressor


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • PGLYRP3 (9606)
  • PGLYRP3 (9598)
  • PGLYRP3 (9913)
  • Pglyrp3 (10090)
  • Pglyrp3 (10116)
  • Pglyrp3b (10116)
  • PGRP-LF (7227)

  • Inparanoids
  • ENSMUSP00000035737 (10090)
  • ENSMMUP00000000644 (9544)
  • ENSP00000290722 (9606)



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