Dlc90F

Symbol: Dlc90F
Name: Dynein light chain 90F
Entrez gene ID: 42199
Ensembl gene ID: FBgn0024432
Species: Fly (Taxid: 7227)

Functional description:
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Required for spermatid differentiation. Is not required for polarized transport in rhabdomere development and appears to be a non-essential component of the cytoplasmic dynein complex. [UniProt]

Observation:

Overexpression of Dlc90F in males increases mean and maximum lifespan by 9% and 14% [22366109]



Assays:
Mean: 9
Maximum: 14

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • DYNLT1 (9606)
  • DYNLT1 (9598)
  • LOC612201 (9615)
  • DYNLT1 (9913)
  • Dynlt1b (10090)
  • Dynlt1f (10090)
  • Dynlt1-ps1 (10090)
  • Dynlt1c (10090)
  • Dynlt1e (10090)
  • Dynlt1d (10090)
  • Dynlt1 (10116)
  • DYNLT1 (9031)
  • si:dkey-148f10.4 (7955)
  • Dlc90F (7227)
  • AgaP_AGAP001229 (7165)

  • Inparanoids
  • FBpp0082996 (7227)
  • ENSMUSP00000090644 (10090)
  • ENSRNOP00000024656 (10116)
  • ENSMMUP00000025567 (9544)
  • ENSP00000356056 (9606)
  • SPAC1805.08 (4896)



  • Edit \ Update (Admin) | Delete

    Comment on This Data Unit