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Symbol: CG10383 Alias: CG10383-PA Entrez gene ID: 35123 Ensembl gene ID: FBgn0032699 Species: Fly (Taxid: 7227) Functional description: CG10383 gene product from transcript CG10383-RA; This gene is referred to in FlyBase by the symbol Dmel\CG10383 (FBgn0032699). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: binding; hydrolase activity, acting on ester bonds. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: GPI anchor metabolic process; intracellular protein transport. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Armadillo-like helical; Armadillo-type fold; GPI inositol-deacylase PGAP1-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 and 18-24 hour embryonic stages, during late pupal stages, in adult male stages. [FlyBase] Observation: Overexpression of CG10383 in males increases mean and maximum lifespan by 12% and 8%, respectively [22366109]. Interventions: Assays: Organismal Lifespan Mean: +12 Maximum: +8 Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Inparanoids Edit \ Update (Admin) | Delete |
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