CG33138

Symbol: CG33138
Alias: CG33138-PA
Entrez gene ID: 326264
Ensembl gene ID: FBgn0053138
Species: Fly (Taxid: 7227)

Functional description:
CG33138 gene product from transcript CG33138-RA; This gene is referred to in FlyBase by the symbol Dmel\CG33138 (FBgn0053138). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: 1,4-alpha-glucan branching enzyme activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: glycogen biosynthetic process. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: 1,4-alpha-glucan-branching enzyme; Alpha amylase; Alpha-amylase, C-terminal all beta; Glycoside hydrolase, family 13, N-terminal; Glycoside hydrolase, subgroup, catalytic domain; Glycoside hydrolase, superfamily; Glycosyl hydrolase, family 13, all-beta; Glycosyl hydrolase, family 13, catalytic domain; Immunoglobulin E-set; Immunoglobulin-like fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed in adults stages of both sexes. [FlyBase]

Observation:

Overexpression of CG33138 in males increased mean lifespan by 11% [22366109].



Assays:
Mean: 11

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • GBE1 (9606)
  • GBE1 (9598)
  • GBE1 (9615)
  • GBE1 (9913)
  • Gbe1 (10090)
  • Gbe1 (10116)
  • GBE1 (9031)
  • LOC100333665 (7955)
  • CG33138 (7227)
  • AgaP_AGAP010428 (7165)
  • T04A8.7 (6239)
  • GLC3 (4932)
  • KLLA0A11176g (28985)
  • AGOS_AEL044W (33169)
  • GeneID:2676993 (148305)
  • NCU05429 (5141)
  • SBE2.1 (3702)
  • SBE2.2 (3702)
  • Os02g0528200 (4530)

  • Inparanoids
  • FBpp0086845 (7227)
  • ENSMUSP00000023393 (10090)
  • ENSRNOP00000039448 (10116)
  • ENSMMUP00000020880 (9544)
  • ENSP00000264326 (9606)
  • YEL011W (4932)



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