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Symbol: SIFR Name: SIFamide receptor Alias: CG10823-PA;CG10823-PB;CG10823-PC;SIFR-PA;SIFR-PB;SIFR-PC;SIFamide-receptor Entrez gene ID: 42530 Ensembl gene ID: FBgn0038880 Species: Fly (Taxid: 7227) Functional description: SIFamide receptor; SIFamide receptor [Source:FlyBase gene name;Acc:FBgn0038880] [Ensembl]; The gene SIFamide receptor is referred to in FlyBase by the symbol Dmel\SIFR (CG10823, FBgn0038880). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: neuropeptide receptor activity. Based on sequence similarity, it is predicted to be involved in the biological process: G-protein coupled receptor signaling pathway. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: GPCR, rhodopsin-like superfamily; GPCR, rhodopsin-like, 7TM; Neuropeptide Y receptor. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed during late pupal stages. [FlyBase] Observation: Overexpression of SIFR in males extends mean and maximum lifespan by 23% and 3%, respectively [22366109]. Interventions: Assays: Organismal Lifespan Mean: +23 Maximum: +3 Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Inparanoids Edit \ Update (Admin) | Delete |
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