Symbol: sm Name: smooth Alias: CG9218-PA;CG9218-PB;CG9218-PE;CG9218-PG;CG9218-PH;CG9218-PI;sm-PA;sm-PB;sm-PE;sm-PG;sm-PH;sm-PI Entrez gene ID: 37254 Ensembl gene ID: FBgn0003435 Species: Fly (Taxid: 7227) Functional description: smooth; smooth [Source:FlyBase gene name;Acc:FBgn0003435] [Ensembl]; The gene smooth is referred to in FlyBase by the symbol Dmel\sm (CG9218, FBgn0003435). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: mRNA binding. There is experimental evidence that it is involved in the biological process: axon guidance; adult feeding behavior. 28 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; macrochaeta; abdominal sternite bristle; acrostichal bristle; scutellar bristle; microchaeta. It has 20 annotated transcripts and 20 annotated polypeptides. Protein features are: Nucleotide-binding, alpha-beta plait; RNA recognition motif domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed in adult male stages. [FlyBase] Observation: Overexpression of sm in males increases mean and maximum lifespan by 29% and and 16%, respectively [22366109]. Interventions: Assays: Organismal Lifespan Mean: +29 Median: +16 Classification: Aging Relevance Analysis/Source: Homologs Inparanoids Edit \ Update (Admin) | Delete |
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