PRE9

Symbol: PRE9
Name: PRoteinase yscE 9
Entrez gene ID: 853036
Ensembl gene ID: YGR135W
Species: Yeast (Taxid: 4932)

Functional description:
Pre9p; Alpha 3 subunit of the 20S proteasome, the only nonessential 20S subunit; may be replaced by the alpha 4 subunit (Pre6p) under stress conditions to create a more active proteasomal isoform [Source:SGD;Acc:S000003367] [Ensembl]

Observation:

Deletion of PRE9 decreases mean and maximum lifespan by 20 - 34% and 2 - 14%, resptectively [21931558].



Assays:
Mean: -20-34
Maximum: -2-14

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • PSMA4 (9606)
  • PSMA4 (9598)
  • PSMA4 (9615)
  • PSMA4 (9913)
  • Psma4 (10090)
  • Psma4 (10116)
  • PSMA4 (9031)
  • psma4 (7955)
  • Pros29 (7227)
  • AgaP_AGAP004960 (7165)
  • pas-3 (6239)
  • SPAC13C5.01c (4896)
  • PRE9 (4932)
  • KLLA0E03917g (28985)
  • AGOS_AFR318W (33169)
  • GeneID:2678637 (148305)
  • NCU05942 (5141)
  • PAC1 (3702)
  • Os06g0167600 (4530)
  • Os06g0176000 (4530)
  • PF13_0282 (5833)



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