|
Symbol: RPT2 Name: Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase Alias: YHS4;YTA5 Entrez gene ID: 851557 Ensembl gene ID: YDL007W Species: Yeast (Taxid: 4932) Functional description: Rpt2p; One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for normal peptide hydrolysis by the core 20S particle [Source:SGD;Acc:S000002165] [Ensembl] Observation: Mutation of RPT2 decreases mean (-68%) and maximum (-53%) replicative lifespan [21931558]. Assays: Mean: -55 Maximum: -42 Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
Comment on This Data Unit