Denigma

crh-1

Symbol: crh-1
Name: CREB Homolog 1
Entrez gene ID: 176597
Ensembl gene ID: Y41C4A.4
Species: Worm (Taxid: 6239)

Functional description:
Protein CRH-1; CREB Homolog family member (crh-1) [Source:RefSeq peptide;Acc:NP_001022861] [Ensembl]

Observation:

RNAi of crh-1 starting at hatching or at adulthood in L4 increases lifespan to a similiar extent [21331044].



Interventions:
  • crh-1 RNAi

    • Assays: Organismal Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


    • References:
  • 21331044: Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • CREM (9606)
  • CREM (9598)
  • CREM (9615)
  • CREM (9913)
  • si:dkey-177e13.4 (7955)
  • crh-1 (6239)



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