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Symbol: ATG1 Name: AuTophaGy related 11 Alias: APG1; AUT3; CVT10 Entrez gene ID: 852695 Ensembl gene ID: YGL180W Species: Yeast (Taxid: 4932) Functional description: Atg1p; Protein ser/thr kinase required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p [Source:SGD;Acc:S000003148] [Ensembl] Observation: ATG1 deletion reduces chronological lifespan by 70% [19302372]. Deletion of ATG1 reduces replicative lifespan by 20% in the alpha strain [18340043]. Interventions: Assays: Replicative Lifespan Chronological Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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