YSC84

Symbol: YSC84
Alias: LSB4
Entrez gene ID: 856409
Ensembl gene ID: YHR016C
Species: Yeast (Taxid: 4932)

Functional description:
Ysc84p; Actin-binding protein involved in bundling of actin filaments and endocytosis of actin cortical patches; activity stimulated by Las17p; contains SH3 domain similar to Rvs167p [Source:SGD;Acc:S000001058] [Ensembl]

Observation:

Deletion of YSC84 increases replicative lifespan by 20% in the alpha strain [19030232]. YSC84 deletion increases replicative lifespan by 25% in the alpha strain [18340043].



Interventions:
  • YSC84 deletion +20 to +25%

  • Assays: Replicative Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • SH3YL1 (9606)
  • LOC606804 (9615)
  • SH3YL1 (9913)
  • Sh3yl1 (10090)
  • Sh3yl1 (10116)
  • SH3YL1 (9031)
  • sb:cb1095 (7955)
  • SPAPJ696.02 (4896)
  • YSC84 (4932)
  • LSB3 (4932)
  • KLLA0A08360g (28985)
  • AGOS_AEL017W (33169)
  • GeneID:2681603 (148305)
  • NCU03888 (5141)



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