Denigma

YPT7

Symbol: YPT7
Name: Yeast Protein Two 7
Alias: VAM4;AST4
Entrez gene ID: 855012
Ensembl gene ID: YML001W
Species: Yeast (Taxid: 4932)

Functional description:
Ypt7p; Rab family GTPase; GTP-binding protein of the rab family; required for homotypic fusion event in vacuole inheritance, for endosome-endosome fusion, similar to mammalian Rab7 [Source:SGD;Acc:S000004460] [Ensembl]

Observation:

YPT7 deletion decreases replicative lifespan by 15% in the alpha strain [18340043]. Deletion of YPT7 cancels out replicative lifespan extension of 0.5% glucose restriction and results under DR also into a shorter replicative lifespan than under AL [18690010].



Interventions:
  • YPT7 deletion -15%

    • Assays: Replicative Lifespan

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor
  • DR-Essential


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • RAB7A (9606)
  • RAB7A (9598)
  • RAB7A (9615)
  • RAB7A (9913)
  • Rab7 (10090)
  • Rab7a (10116)
  • RAB7A (9031)
  • rab7 (7955)
  • Rab7 (7227)
  • AgaP_AGAP001617 (7165)
  • rab-7 (6239)
  • ypt7 (4896)
  • YPT7 (4932)
  • KLLA0D01265g (28985)
  • AGOS_ACR003C (33169)
  • GeneID:2678359 (148305)
  • NCU03711 (5141)
  • RABG3E (3702)
  • ATRAB7B (3702)
  • Os05g0516600 (4530)

    • Orthologs
  • RAB38 (9606)
  • Rabl2b (10116)
  • Rab32 (10090)
  • Rab7a (10116)
  • LOC720911 (9544)
  • RABL2A (9606)
  • RABL2B (9606)
  • RAB9A (9606)
  • Rab9b (10090)
  • RAB38 (9544)
  • ltd (7227)
  • RAB32 (9544)
  • Rab9b (10116)
  • Rab32 (10116)
  • RAB9B (9606)
  • RAB7B (9544)
  • Rab9 (10090)
  • glo-1 (6239)
  • RAB9B (9544)
  • RAB7A (9606)
  • Rab9 (7227)
  • Rab7 (7227)
  • ypt7 (4896)
  • Rab7b (10116)
  • RAB32 (9606)
  • RAB7L1 (9606)
  • RABL2B (9544)
  • Rabl2 (10090)
  • Rab9a (10116)
  • Rab38 (10090)
  • rab-7 (6239)
  • Rab38 (10116)
  • 5430435G22Rik (10090)
  • Rab7l1 (10090)
  • RAB7L1 (9544)
  • Rab7 (10090)
  • RAB38 (9606)
  • Rabl2b (10116)
  • Rab32 (10090)
  • Rab7a (10116)
  • LOC720911 (9544)
  • RABL2A (9606)
  • RABL2B (9606)
  • RAB9A (9606)
  • Rab9b (10090)
  • RAB38 (9544)
  • ltd (7227)
  • RAB32 (9544)
  • Rab9b (10116)
  • Rab32 (10116)
  • RAB9B (9606)
  • RAB7B (9544)
  • Rab9 (10090)
  • glo-1 (6239)
  • RAB9B (9544)
  • RAB7A (9606)
  • Rab9 (7227)
  • Rab7 (7227)
  • ypt7 (4896)
  • Rab7b (10116)
  • RAB32 (9606)
  • RAB7L1 (9606)
  • RABL2B (9544)
  • Rabl2 (10090)
  • Rab9a (10116)
  • Rab38 (10090)
  • rab-7 (6239)
  • Rab38 (10116)
  • 5430435G22Rik (10090)
  • Rab7l1 (10090)
  • RAB7L1 (9544)
  • Rab7 (10090)



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