SYH1

Symbol: SYH1
Name: Protein of unknown function that may interact with ribosomes, based on co-purification experiments; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
Alias: MYR1
Entrez gene ID: 855999
Ensembl gene ID: YPL105C
Species: Yeast (Taxid: 4932)

Functional description:
Syh1p; Protein of unknown function that influences nuclear pore distribution; co-purifies with ribosomes; contains a GYF domain, which bind proline-rich sequences; deletion extends chronological lifespan [Source:SGD;Acc:S000006026] [Ensembl]

Observation:

Deletion of SYH1 decreases replicative lifespan by 20% in the alpha strain [18340043], but increases chronological lifespan by 16 - 73% (16, 16, 73) in diploid cells [21447998].



Assays:
Mean: +16-73

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • SMY2 (4932)
  • SYH1 (4932)
  • KLLA0E24531g (28985)
  • AGOS_AGR209W (33169)



  • Edit \ Update (Admin) | Delete

    Comment on This Data Unit