YPC1

Symbol: YPC1
Name: Yeast Phyto-Ceramidase 1
Entrez gene ID: 852481
Ensembl gene ID: YBR183W
Species: Yeast (Taxid: 4932)

Functional description:
Ypc1p; Alkaline ceramidase that also has reverse (CoA-independent) ceramide synthase activity, catalyzes both breakdown and synthesis of phytoceramide; overexpression confers fumonisin B1 resistance [Source:SGD;Acc:S000000387] [Ensembl]

Observation:

Deletion of YPC1 decreases replicative lifespan by 15% in the alpha strain [19030232].



Interventions:
  • YPC1 deletion -15%

  • Assays: Replicative Lifespan

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • ACER3 (9606)
  • ACER3 (9598)
  • ACER3 (9615)
  • ACER3 (9913)
  • Acer3 (10090)
  • Acer3 (10116)
  • PHCA (9031)
  • LOC555411 (7955)
  • YDC1 (4932)
  • YPC1 (4932)
  • KLLA0E23981g (28985)
  • GeneID:2675865 (148305)
  • NCU02969 (5141)
  • ATCES1 (3702)
  • Os03g0698900 (4530)



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