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Symbol: TDA5 Name: Topoisomerase I Damage Affected 5 Entrez gene ID: 851146 Ensembl gene ID: YLR426W Species: Yeast (Taxid: 4932) Functional description: hypothetical protein; Putative protein of unknown function; detected in highly purified mitochondria in high-throughput studies; proposed to be involved in resistance to mechlorethamine and streptozotocin; null mutant sensitive to expression of top1-T722A allele [Source:SGD;Acc:S000004418] [Ensembl] Observation: Deletion of TDA5 decreases replicative lifespan by 30% in the alpha strain [19030232]. Interventions: Assays: Replicative Lifespan Maximum: Deletion Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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