Denigma: Factor

YDR248C

Symbol: YDR248C
Entrez gene ID: 851835
Ensembl gene ID: YDR248C
Species: Yeast (Taxid: 4932)

Functional description:
hypothetical protein; Putative protein of unknown function; sequence similarity to bacterial and human gluconokinase; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; upregulated by deletion of the RNAP-II associated factor, PAF1 [Source:SGD;Acc:S000002656] [Ensembl]

Observation:

Deletion of YDR248C increases replicative lifespan by 20% in the alpha strain [19030232].

Interventions:

YDR248C deletion +20%

Assays: Replicative Lifespan

Classification:

Gerontogene

Positive Gerontogene

Aging Relevance Analysis/Source:

GenAge