WSC4

Symbol: WSC4
Name: cell Wall integrity and Stress response Component 4
Alias: YHC8; YFW1
Entrez gene ID: 856357
Ensembl gene ID: YHL028W
Species: Yeast (Taxid: 4932)

Functional description:
Wsc4p; ER membrane protein involved in the translocation of soluble secretory proteins and insertion of membrane proteins into the ER membrane; may also have a role in the stress response but has only partial functional overlap with WSC1-3 [Source:SGD;Acc:S000001020] [Ensembl]

Observation:

Deletion of WSC4 decreases replicative lifespan by 30% in the alpha strain [18340043].



Interventions:
  • WSC4 deletion -30%

  • Assays: Replicative Lifespan

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • wsc1 (4896)
  • WSC4 (4932)
  • KLLA0E00771g (28985)
  • AGOS_AFR191C (33169)



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