VHS1

Symbol: VHS1
Name: Viable in a Hal3 Sit4 background 1
Entrez gene ID: 851834
Ensembl gene ID: YDR247W
Species: Yeast (Taxid: 4932)

Functional description:
Vhs1p; Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; homolog of Sks1p [Source:SGD;Acc:S000002655] [Ensembl]

Observation:

Deletion of VHS1 increases replicative lifespan [16293764]. VHS1 deletion increases replicative lifespan by 60% in the alpha strain [19030232].



Interventions:
  • VHS1 deletion +60%

  • Assays: Replicative Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • ran1 (4896)
  • VHS1 (4932)
  • AGOS_ADR163W (33169)
  • GeneID:2675691 (148305)
  • NCU04990 (5141)



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