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Symbol: VAM7 Name: VAcuolar Morphogenesis 7 Alias: VPS43; VPL24 Entrez gene ID: 852660 Ensembl gene ID: YGL212W Species: Yeast (Taxid: 4932) Functional description: Vam7p; Vacuolar SNARE protein that functions with Vam3p in vacuolar protein trafficking; has an N-terminal PX domain (phosphoinositide-binding module) that binds PtdIns-3-P and mediates membrane binding; SNAP-25 homolog [Source:SGD;Acc:S000003180] [Ensembl] Observation: VAM7 deletion decreases replicative lifespan under AL and blocked DR-mediated lifespan extension. Replicative lifespan decreases by 70% on DR in VAM7 deletion mutant [18690010]. Interventions: Assays: Replicative Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Orthologs Edit \ Update (Admin) | Delete |
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