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Symbol: TPK1 Name: Takashi's Protein Kinase 1 Alias: PKA1;SRA3 Entrez gene ID: 853275 Ensembl gene ID: YJL164C Species: Yeast (Taxid: 4932) Functional description: Tpk1p; cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk2p and Tpk3p [Source:SGD;Acc:S000003700] [Ensembl] Observation: Deletion of TPK1 decreases replicative lifespan by 40% in the alpha strain [18340043] as well as chronological lifespan [21447998]. Assays: Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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