SWD3

Symbol: SWD3
Name: Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5
Entrez gene ID: 852472
Species: Yeast (Taxid: 4932)

Functional description:
Swd3p; Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5 [Source:SGD;Acc:S000000379] [Ensembl]

Observation:

Replicative lifespan decreased by 15% in the alpha strain



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • SWD3 (4932)
  • KLLA0E24487g (28985)
  • AGOS_AGR207C (33169)



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