Symbol: SWD3 Name: Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5 Entrez gene ID: 852472 Species: Yeast (Taxid: 4932) Functional description: Swd3p; Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5 [Source:SGD;Acc:S000000379] [Ensembl] Observation: Replicative lifespan decreased by 15% in the alpha strain Assays: Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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