SAS3

Symbol: SAS3
Name: Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; sas3 gcn5 double mutation confers lethality
Entrez gene ID: 852228
Species: Yeast (Taxid: 4932)

Functional description:
Sas3p; Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; mutant has aneuploidy tolerance; sas3gcn5 double mutation is lethal [Source:SGD;Acc:S000000148] [Ensembl]

Observation:

Survival increased during early chronological aging (day 5-15);



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • SAS3 (4932)
  • KLLA0E19911g (28985)
  • AGOS_ACR236W (33169)



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