RTT107

Symbol: RTT107
Name: Protein implicated in Mms22-dependent DNA repair during S phase, DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition
Entrez gene ID: 856559
Species: Yeast (Taxid: 4932)

Functional description:
Rtt107p; Protein implicated in Mms22-dependent DNA repair during S phase; involved in recruiting the SMC5/6 complex to double-strand breaks; DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BR /.../ains; has a role in regulation of Ty1 transposition [Source:SGD;Acc:S000001197] [Ensembl]; Protein implicated in Mms22-dependent DNA repair during S phase; involved in recruiting the SMC5/6 complex to double-strand breaks; DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition [SGD]

Observation:

Replicative lifespan decreased by 30% in the alpha strain



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • brc1 (4896)
  • RTT107 (4932)
  • KLLA0E15621g (28985)
  • AGOS_ADL145C (33169)
  • GeneID:2674585 (148305)
  • NCU03924 (5141)



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