Denigma

RPS27B

Symbol: RPS27B
Name: Ribosomal Protein of the Small subunit 27B
Alias: S27B; YS20; rp6
Entrez gene ID: 856415
Ensembl gene ID: YHR021C
Species: Yeast (Taxid: 4932)

Functional description:
Rps27bp; Protein component of the small (40S) ribosomal subunit; nearly identical to Rps27Ap and has similarity to rat S27 ribosomal protein [Source:SGD;Acc:S000001063] [Ensembl]

Observation:

Deletion of RPS27B decreases mean replicative lifespan decreased by 20 - 30% in the alpha strain [18423200; 19030232] and by 27% in the ORF collection as well as by 14% in the remade strain [22377630].



Interventions:
  • RPS27B deletion -14 to -30%

    • Assays: Replicative Lifespan

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • RPS27 (9606)
  • RPS27 (9598)
  • RPS27 (9615)
  • Gm9846 (10090)
  • Rps27 (10090)
  • Rps27 (10116)
  • zgc:109888 (7955)
  • zgc:73262 (7955)
  • RpS27 (7227)
  • AgaP_AGAP007157 (7165)
  • rps-27 (6239)
  • rps27 (4896)
  • RPS27B (4932)
  • RPS27A (4932)
  • KLLA0E11661g (28985)
  • AGOS_ACR065C (33169)
  • GeneID:2682425 (148305)
  • NCU00618 (5141)
  • ARS27A (3702)
  • AT2G45710 (3702)
  • AT5G47930 (3702)
  • Os04g0346100 (4530)
  • Os02g0478700 (4530)
  • PF13_0045 (5833)



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