Symbol: RPS11A Name: Ribosomal Protein of the Small subunit 11A Alias: S11A;S18A;YS12;rp41A Entrez gene ID: 851589 Ensembl gene ID: YDR025W Species: Yeast (Taxid: 4932) Functional description: Rps11ap; Protein component of the small (40S) ribosomal subunit; identical to Rps11Bp and has similarity to E. coli S17 and rat S11 ribosomal proteins [Source:SGD;Acc:S000002432] [Ensembl] Observation: Deletion of RPS11A increases mean replicative lifespan by 30% in alpha strain [18340043; 18423200] and by 28% in the ORF collection, but non-significantly decreases mean replicative lifespan by 7% in the remade strain [22377630]. Its deletion also increases mean chronological lifespan by 35 - 48% (34, 36, 48) in diploid cells [21447998]. Assays: Mean: +28-30 Classification: Aging Relevance Analysis/Source: Homologs Note: non-significantly decreases mean replicative lifespan by 7% in the remade strain. Edit \ Update (Admin) | Delete |
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