RPL4A

Symbol: RPL4A
Name: Ribosomal Protein of the Large subunit 4A
Entrez gene ID: 852319
Ensembl gene ID: YBR031W
Species: Yeast (Taxid: 4932)

Functional description:
Rpl4ap; N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl4Bp and has similarity to E. coli L4 and rat L4 ribosomal proteins [Source:SGD;Acc:S000000235] [Ensembl]

Observation:

Deletion of RPL4A increases replicative lifespan by 15% in the alpha strain [18340043]. RPL4A deletion increases replicative lifespan by 20% in the alpha strain [18423200].



Interventions:
  • RPL4A deletion +15 to +20%

  • Assays: Replicative Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • LOC478348 (9615)
  • LOC609491 (9615)
  • LOC610395 (9615)
  • LOC608310 (9615)
  • LOC507271 (9913)
  • rpl401 (4896)
  • rpl402 (4896)
  • RPL4A (4932)
  • RPL4B (4932)
  • KLLA0B07139g (28985)
  • AGOS_AAR191C (33169)
  • GeneID:2678306 (148305)
  • NCU03757 (5141)



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